How BLD Helps

Applications of Oxazoline Ligands in Asymmetric Catalysis

29 June 2022

Recommended Products View More

Oxazoline ligands currently dominate in asymmetric synthesis, they have been extensively applied in a series of important metal-catalyzed enantioselective reactions.

Technical Notes:

Nickel/Photo-Cocatalyzed Asymmetric Acyl-Carbamoylation of Alkenes.[1]

Asymmetric Ni-Catalyzed Radical Relayed Reductive Coupling.[2]

Modular access to substituted cyclohexanes with kinetic stereocontrol.[3]

Enantioselective Electrocatalytic Cyanofunctionalization of Vinylarenes.[4]

Asymmetric Allylic C-H Alkylation via Palladium(II)/cis-ArSOX Catalysis.[5]

Available Ligands in BLDpharm.

1.PyOX Series

2.BOX Series

3.PHOX Series

4.SOX Series


[1]J. Am. Chem. Soc. 2020, 142, 2180.

[2]J. Am. Chem. Soc2020, 142, 13515.

[3]Science2022, 376, 749.

[4]J. Am. Chem. Soc2019, 141, 14480.

[5]J. Am. Chem. Soc2018, 140, 10658.